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Beyond Static Assays

Resolving Dynamic Biomolecular Transitions

Our platform unlocks previously inaccessible cellular signaling and structural transition data to accelerate drug discovery for complex disease targets. We map real-time interactions conventional methods miss.

— Mechanistic Resolution

Visualizing the intricate dance of DNA strand displacement, revealing the conformational shifts that govern genomic stability.

Our Method

Dynamic Profiling: From Molecule to Mechanism

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Molecular Immobilization

High-Frequency Signal Capture

Kinetic & Structural Resolution

Precise immobilization of biomolecules onto proprietary surfaces, maintaining native structure and dynamic freedom for real-time observation.

Optical and biophysical tracking systems capture conformational state shifts at sub-millisecond resolution, revealing transient interactions.

Advanced computational models translate raw data into validated kinetic parameters and refined 3D structural topologies, identifying novel targets.

Uncovering Novel Targets

Alternative DNA Structures and Cellular Pathways

Non-canonical DNA structures like G-quadruplexes and R-loops govern master switches in genomic stability. Our technology provides unprecedented access to these fleeting, yet critical, interactions.

Transient protein-protein interactions form fleeting signaling nodes undetectable by conventional crystal structure assays. We quantify these dynamic events, providing mechanistic insights into cellular trafficking and disease progression.

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Advance Your Research with Dynoma

Partner with us to accelerate your drug discovery programs and unlock the full potential of dynamic biology.